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Drug shows promise in 1st largely minority COVID-19 study

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A drug company said Friday that a medicine it sells to tamp down inflammation has helped prevent the need for breathing machines in hospitalized COVID-19 patients in the first large study that primarily enrolled Hispanics and Blacks.

Switzerland-based Roche reported the results for tocilizumab, sold now as Actemra and RoActemra for treating rheumatoid arthritis and some other diseases. The company said it would quickly publish the results, which have not yet been reviewed by independent scientists, and would speak with regulators about next steps.

The drug, given through an IV, tamps down a protein called interleukin-6 that’s often found in excess in COVID-19 patients. It failed in a previous study that tested it in people more severely ill from the coronavirus. The new study was done in the United States, South Africa, Kenya, Brazil, Mexico and Peru. About 85% of the 389 participants were Hispanic, Black, Native American or other ethnic or racial minorities. These groups have been disproportionately hurt by the pandemic. ...

 
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