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UPDATE: Global health suggest AstraZeneca vaccine alarm from South Africa study was premature.rings alarm

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GENEVA (Reuters) - Health officials around the world gave their backing to the AstraZeneca vaccine against COVID-19, after a study showing it had little effect against mild disease caused by the variant now spreading quickly in South Africa rang global alarm.

The prospect that new virus variants could evolve the ability to elude vaccines is one of the main risks hanging over the global strategy to emerge from the pandemic by rolling out vaccines this year.

South Africa, where a new variant now accounts for the vast bulk of cases, initially announced a pause in its rollout of a million doses of the AstraZeneca vaccine.

But it said on Monday it could still roll it out in a “stepped manner”, giving out 100,000 doses and monitoring it to see if it prevents hospitalisations and deaths.

“It is vastly too early to be dismissing this vaccine,” said Richard Hatchett, CEO of the Coalition for Epidemic Preparedness Innovations, a foundation that co-leads the global COVAX programme to provide vaccine doses in poor countries. ...

Professor Salim Abdool Karim, co-chair of South Africa’s Ministerial Advisory Committee on COVID-19, said it was too early to conclude that the AstraZeneca would not prevent serious disease caused by the variant prevalent there. ...

The overall message from the World Health Organization and others was: don’t panic. Several global health officials noted that the South African study was small and had tested the vaccine using a short four-week interval between the first and second doses, despite evidence having since emerged that it works better if there is a longer wait. ...

 

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