It begins with a mild fever and malaise, followed by a painful cough and shortness of breath. The infection prospers in crowds, spreading to people in close reach. Containing an outbreak requires contact tracing, as well as isolation and treatment of the sick for weeks or months.

This insidious disease has touched every part of the globe. It is tuberculosis, the biggest infectious-disease killer worldwide, claiming 1.5 million lives each year.

An experimental coronavirus vaccine developed by Johnson & Johnson protected monkeys from infection in a new study. It is the second vaccine candidate to show promising results in monkeys this week.

The company recently began a clinical trial in Europe and the United States to test its vaccine in people. It is one of more than 30 human trials for coronavirus vaccines underway across the world. But until these trials are complete — which will probably take several months — the monkey data offers the best clues to whether the vaccines will work.

As schools, universities and businesses struggle to reopen without the coronavirus testing they need to curb outbreaks, the Trump administration’s testing czar testified to Congress Friday that it was currently impossible to get all tests back within three days.

The testing czar, Adm. Brett P. Giroir, told lawmakers that getting all coronavirus tests back between 48 and 72 hours, which many health officials have said is critical, “is not a possible benchmark we can achieve today, given the demand and the supply.”

ROME — When the coronavirus erupted in the West, Italy was the nightmarish epicenter, a place to avoid at all costs and a shorthand in the United States and much of Europe for uncontrolled contagion.