A new analysis suggests that the Omicron variant has comparable intrinsic severity to the ancestral (Wuhan) SARS-CoV-2 strain, but its effective severity is substantially lower because of vaccination.
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Case-patients with at least one dose of Pfizer-BioNTech or CoronaVac vaccine had significantly lower odds of mortality than unvaccinated patients, the authors said, with the lowest odds observed in people who had received three Pfizer doses (odds ratio, 0.31; 95% CI, 0.18 to 0.49).
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