The Food and Drug Administration’s scientists confirmed that overall the vaccine is about 66% effective at preventing moderate to severe COVID-19. The agency also said J&J’s shot — one that could help speed vaccinations by requiring just one dose instead of two — is safe to use.

That’s just one step in the FDA’s evaluation of a third vaccine option for the U.S. On Friday, the agency’s independent advisers will debate if the evidence is strong enough to recommend the long-anticipated shot. Armed with that advice, FDA is expected to make a final decision within days. ...

BUDAPEST — Officials in Hungary are urging people to trust in the vaccines already approved by the country ahead of a planned rollout Wednesday of a COVID-19 vaccine developed in China.

LONDON (AP) — Two U.K. studies released Monday showed that COVID-19 vaccination programs are contributing to a sharp drop in hospitalizations, boosting hopes that the shots will work as well in the real world as they have in carefully controlled studies.

Preliminary results from a study in Scotland found that the Pfizer-BioNTech vaccine reduced hospital admissions by up to 85% four weeks after the first dose, while the Oxford-AstraZeneca shot cut admissions by up to 94%. In England, preliminary data from a study of health care workers showed that the Pfizer vaccine reduced the risk of catching COVID-19 by 70% after one dose, a figure that rose to 85% after the second.